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HLA types detection

　　The HLA (human leukocyte antigen) : human leukocyte antigen, from the human gene complex coding chromosome 6 short arm, is the most complicated part of the human body known genetic polymorphism system, expressed in the human body cell membrane surface, on behalf of HLA antigen specificity of each individual is closely related to the body's immune system, is the main antigen mediated graft rejection.


檢測(cè)項(xiàng)目檢測(cè)方法
HLA-A/B/DR位點(diǎn)中分辨PCR-SSP
HLA-A/B/DR位點(diǎn)中分辨PCR-SBT
HLA-CW/DQ位點(diǎn)高分辨PCR-SBT
HLA-A/B/DR/CW/DQ位點(diǎn)高分辨PCR-SBT


Product introduction

HLA is the main antigen of the graft rejection, and the survival rate of graft depends on the degree of consistency of HLA type between donor and recipient. At present, our company is mainly by PCR sequence specific primers amplification technology (squence specific primer, PCR-SSP) and PCR direct sequence analysis of gene typing technique (sequence based were, PCR-SBT) two kinds of methods to judge for both the consistency degree, for clinical diagnosis and transplantation and in the treatment to provide guidance.



HLA分型產(chǎn)品流程

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Advantage of HLA parting with previous analysis means? 

Serum credits as previous general classification method, because it has the characteristics of simple, fast, the disadvantage is that classification rate is very low, sometimes is not easy to obtain the relevant classification of serum, and cannot ensure the donor and HLA matching real patients. Now basically is to use molecular biology method, commonly used is the PCR - SSP or PCR - SBT method. Its detection method in detecting flux, data quality, cost control, etc have a qualitative leap, and high resolution database